Lipopolysaccharide Preconditioning Protects Hepatocytes from Ischemia/Reperfusion Injury (IRI) through Inhibiting ATF4-CHOP Pathway in Mice
Figure 5
ATF4 knockdown protection against hepatocellular death induced by H2O2 in vitro.
(A) Western-assisted analysis of ATF4, CHOP, Cleaved Caspase-12, Cleaved Caspase-3 and β-Actin. Representative of three experiments. (B) Relative quantities of protein of ATF4, CHOP, Cleaved Caspase-12 and Cleaved Caspase-3 to β-Actin, Mean±SD, **P<0.001 or *P<0.05 versus CONsiRNA. (C)The released LDH level of hepatocytes after H2O2 treatment, **P<0.001 versus CONsiRNA.