< Back to Article

A Unified Framework for Association Analysis with Multiple Related Phenotypes

Figure 3

Comparison of Bayes Factors in simple bivariate simulations, correlation = 0.4.

The upper panel shows a typical simulated dataset under each of three scenarios (see text), but with effect sizes increased to aid clarity; each dot represents a single individual, colored according to genotype. Note that in the middle scenario only is associated with genotype. The lower panel compares and with a reference BF, which is the theoretical optimal for that simulation scenario. Thus one can see not only how the BFs compare with each other, but also the extent to which they lose compared with the optimal. Each point represents the results from a single simulation, and each simulation is represented by three points.

doi: https://doi.org/10.1371/journal.pone.0065245.g003