3-Oxoacyl-ACP Reductase from Schistosoma japonicum: Integrated In Silico-In Vitro Strategy for Discovering Antischistosomal Lead Compounds
Figure 5
Optical microscopy of worms exposed to compounds 19, 22 and 27.
A. The morphology of worms treated with 2% DMSO for 72 h. B. The morphology of worms treated with 10 µg/ml of OAR19 for 48 h. C. The morphology of worms treated with 10 µg/ml of OAR22 for 48 h. D. The morphology of worms treated with 40 µg/ml of OAR27 for 24 h. E. The morphology of worms treated with 10 µg/ml of PZQ for 24 h.