Diffusion Weighted Imaging Evaluated the Early Therapy Effect of Tamoxifen in an MNU-Induced Mammary Cancer Rat Model
Figure 4
Histological analysis of tumor response following tamoxifen therapy.
(A) Representative microphotographs of tamoxifen sensitive, intermediate, and resistant tumor tissues with TUNEL, Ki-67, ERα, and ERβ staining, while the target cells were indicated with black arrows. (B) Apoptotic (TUNEL), (C) proliferative (Ki-67), (D) ERα-positive, and (E) ERβ-positive cell densities of the three groups. Statistical difference from resistant group is represented with asterisks above bars.