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Diffusion Weighted Imaging Evaluated the Early Therapy Effect of Tamoxifen in an MNU-Induced Mammary Cancer Rat Model

Figure 3

Tumor volume and ADC changes following tamoxifen therapy.

(A) Volume changes of tumors sensitive, intermediate, or resistant to tamoxifen over 32 days after therapy initiation, when the initial tumor volumes were normalized to 100%. (B) ADC changes of sensitive, intermediate, or resistant tumors for 7 days after therapy initiation, when the initial ADC values were normalized to 0%. Statistical differences from resistant and intermediate groups are represented with asterisk and hash mark, respectively.

Figure 3

doi: https://doi.org/10.1371/journal.pone.0064445.g003