Retinoic Acid Upregulates Ret and Induces Chain Migration and Population Expansion in Vagal Neural Crest Cells to Colonise the Embryonic Gut
Figure 3
E1.5 VNCC donors are poor at colonising aneural gut in catenary cultures, relative to E4.5 ENCC donors.
Colonisation performance (cell number and chain formation) of QCPN+ cells was quantified on a five point scale (0 = nil to 4 = dense chains and aggregates, in 5 gut regions (MG1, MG2, Ceca, HG1, HG2). Averages are shown. The following shading system was applied: 0.0, white; 0.1–1.4, light gray; 1.5–2.4, medium gray; 2.5–3.4, dark gray; 3.5–4.0, black. * denotes cells in chains or aggregates. E = quail embryonic day, vNT = vagal neural tube, MG = midgut, wg = with gut.