The Effects of p38 MAPK Inhibition Combined with G-CSF Administration on the Hematoimmune System in Mice with Irradiation Injury
Figure 1
Effects of SB and/or G-CSF treatment on BMMNC counts.
Mice were treated with ip injection of vehicle (V), SB 203580 (SB), G-CSF (CSF), or both (C+S) after exposure to 6Gy TBI as described in the Methods. A group of sham-irradiated control mice was included as a control (Ctr). BMMNCs were numerated after the mice were euthanized 10 days (A) and 30 days (B) after TBI. The data are expressed as mean± SD (n = 5). a, p<0.05, vs. Ctr; b, p<0.05, vs. V;c, p<0.05, vs. CSF; d, p<0.05, vs. SB.