Spermine and Citrate as Metabolic Biomarkers for Assessing Prostate Cancer Aggressiveness
Figure 2
Representative HR-MAS spectra and corresponding HES stained prostate tissue samples with different Gleason grades.
Visual inspection of the spectra show decreased levels of polyamines (predominately spermine) and citrate, and increased levels of GPC, PCho, and Cho with increasing tumor grade.