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Murine Cytomegalovirus Immediate-Early 1 Gene Expression Correlates with Increased GVHD after Allogeneic Hematopoietic Cell Transplantation in Recipients Reactivating from Latent Infection

Figure 1

Weight change after MCMV infection and MCMV serology testing.

MCMV infection was done by intraperitoneal injection of 3×104 PFU purified Smith strain in naive BALB/c mice and another set of mice were mock infected as control. (A) Weight change was monitored following infection for 25 weeks; n per group = 28 (MCMV) and 24 (mock); Data are presented as mean. (B) 25 weeks following infection, animals were analyzed for anti-MCMV IgG seropositivity as indicator for MCMV infection. Data shown present the index value with ≥1 determined as positive, data points for individual mice are shown.

Figure 1

doi: https://doi.org/10.1371/journal.pone.0061841.g001