The β-Hemolysin and Intracellular Survival of Streptococcus agalactiae in Human Macrophages
Figure 6
Intracellular S. agalactiae induced cytokine expression in THP-1 macrophages.
THP-1 macrophages were infected with hemolytic (BSU 98) and nonhemolytic (BSU 453) GBS at a MOI of 1∶1 at indicated time points. Extracellular bacteria were killed by antibiotics for an additional 1 h. A) IL-8 and B) TNF-α levels were measured in the supernatant by ELISA. Uninfected cells served as control. Data shown are the mean ± SD of three independent experiments.