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Antifungal Efficacy during Candida krusei Infection in Non-Conventional Models Correlates with the Yeast In Vitro Susceptibility Profile

Figure 9

Effect of antifungal treatment of haemocyte density and melanization of G. mellonella infected with C. krusei or C. albicans.

(A) Hemocytic density of G. mellonella infected with C. albicans SC5314 or C. krusei ATCC 6258 treated with amphotericin B (4 mg/kg) or fluconazole (64 mg/kg). (B) Optical Density (OD) of the haemolymph of G. mellonella infected with C. albicans or C. krusei treated with amphotericin B (4 mg/kg) or with fluconazole (64 mg/kg). Black bars, no treatment; grey bars, fluconazole; white bars, amphotericin B. * p<0.05.

Figure 9

doi: https://doi.org/10.1371/journal.pone.0060047.g009