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Molecular Study of Dietary Heptadecane for the Anti-Inflammatory Modulation of NF-kB in the Aged Kidney

Figure 4

Heptadecane protected YPEN-1 cells from t-BHP-induced oxidative stress and cytotoxicity.

(A) Cells were treated with or without/heptadecane at concentrations of 1, 5, 10, and 20 µM for 1 hr and then with vehicle or 10 µM t-BHP. (B) Cells were treated with or without heptadecane at concentrations of 1, 5, 10 and 20 µM for 1 hr and then with t-BHP (10 µM) for 6 hr. Viable cell numbers were determined using an MTT assay. ##p<0.01 vs. vehicle treated control group; **p<0.01, ***p<0.001 vs. the 10 µM t-BHP group by one-factor ANOVA.

Figure 4

doi: https://doi.org/10.1371/journal.pone.0059316.g004