Molecular Study of Dietary Heptadecane for the Anti-Inflammatory Modulation of NF-kB in the Aged Kidney
Figure 3
Heptadecane suppressed expressions of NF-kB-dependent genes in aged rats.
Western blot was performed to detect renal COX-2 and iNOS levels in cytoplasmic extracts (40 µg protein) from young, aged, and aged rats fed heptadecane. One representative blot of each protein is shown from three experiments that yielded similar results, respectively. Young rats (9 months of age) and aged (20 months of age) were utilized. Heptadecane was fed to aged rats at 2 mg or 4 mg/Kg per day for 10 days. Statistical significance: results of one-factor ANOVA: ***p<0.001 vs. young rat; #p<0.05, ##p<0.01 vs. old non-heptadecane-fed rats, respectively.