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Protein Malnutrition Induces Bone Marrow Mesenchymal Stem Cells Commitment to Adipogenic Differentiation Leading to Hematopoietic Failure

Figure 2

Flow cytometry analyses of the bone marrow of control and malnourished mice.

The selection of gates, R1, for the cell populations that were not labeled with fluorochromes are indicated (SSC in the y-axis vs. FSC in the x-axis). Immunophenotypical bone marrow analysis was carried out in gate R1 for CD117 and CD45 expression. The graphical results are expressed as the means with standard deviations for CD117+ and CD45+ expression by control (n = 6) and malnourished (n = 6) mice. The number in brackets denotes the number of animals used in the experiment. *(p ≤ 0.05) and ***(p ≤ 0.001) indicate where there was a significant difference between the control group and the malnourished group.

Figure 2

doi: https://doi.org/10.1371/journal.pone.0058872.g002