Osbpl8 Deficiency in Mouse Causes an Elevation of High-Density Lipoproteins and Gender-Specific Alterations of Lipid Metabolism
Figure 5
HDL catabolism in Osbpl8KO mice.
Chow-fed WT and Osbpl8KO (n = 4–6) female (A) or male (B) animals were injected with Alexa568-labeled mouse HDL (40 µg protein/animal), and the fluorescence signal (y-axis; mean ± s.e.m., % of starting value at 5 min post-injection) in their plasma as a function of time (x-axis) was measured as specified in Materials and Methods.