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Molecular Basis for Viral Selective Replication in Cancer Cells: Activation of CDK2 by Adenovirus-Induced Cyclin E

Figure 2

Cyclin E/CDK2 complex induced by viral infection in A549 cells.

(A) A549 cell lysates were immunoprecipitated with anti-cyclin E antibody (1:50 dilution). Immunocomplexes were analyzed by Western blot with cyclin E and CDK2 antibodies. (B) The cell lysates were immunoprecipitated with anti-CDK2 antibody and immunoblotted for CDK2, cyclin E and cyclin EL.

Figure 2

doi: https://doi.org/10.1371/journal.pone.0057340.g002