Overexpression of miR -155 Promotes Proliferation and Invasion of Human Laryngeal Squamous Cell Carcinoma via Targeting SOCS1 and STAT3
Figure 5
Figure 5A: The correlation between miR-155 and SOCS1.
The correlation between miR-155 and SOCS1 in 63 tumor and 21 control mucosa specimens were analyzed. MiR-155 had a significant negative correlation with SOCS1 protein. Pearson correlation coefficient was −0.691 (p<0.001). Figure 5B: The correlation between SOCS1 and STAT3. The correlation between SOCS1 and STAT3 in 63 tumor and 21 control mucosa specimens were also analyzed. Significant negative correlation was found between SOCS1 and STAT3. Pearson correlation coefficient was −0.787 (p<0.001). Figure 5C: The correlation between miR-155 and STAT3. The correlation between miR-155 and STAT3 in 63 tumor and 21 control mucosa specimens were analyzed. MiR-155 had a significant positive correlation with STAT3 protein. Pearson correlation coefficient was 0.773 (p<0.001).