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The Therapeutic Effect of Negative Pressure in Treating Femoral Head Necrosis in Rabbits

Figure 7

Femoral head microvascular ink staining images (100× magnification) from each experimental group.

In the model control group, the small number of ink-stained blood vessels were thin and presented primarily in the bone marrow cavity of the femoral head (Figure A). In the normal control group, there were relatively more ink-stained blood vessels with a thick vascular lumen in the bone marrow of the femoral head (Figure D). Compared with the model control group, the core compression group had more ink-stained blood vessels with a thicker vascular lumen in the bone marrow of the femoral head at week 4 (B) and week 8 (C). However, there was no significant difference between week 4 and week 8. In the negative pressure group, the number of ink-stained blood vessels with a thicker vascular lumen in the bone marrow of the femoral head was increased significantly at week 4 (E) and week 8 (F). Compared with week 4, there was significant improvement at week 8, and the parameters at both time points were superior to those of the normal control group.

Figure 7

doi: https://doi.org/10.1371/journal.pone.0055745.g007