Thermally Targeted Delivery of a c-Myc Inhibitory Polypeptide Inhibits Tumor Progression and Extends Survival in a Rat Glioma Model
Figure 3
Inhibition of Glioma Cell Proliferation by CPP-ELP-H1 Polypeptides in vitro.
C6 cells were exposed to various concentrations of Bac-ELP1-H1 (A) or SynB1-ELP1-H1 (B) at 37°C or 42°C for 1 h, and cell number was determined 72 h later. C. C6, D54, or U-87 MG cells were exposed to 40 µM Bac-ELP1-H1 for 1 h at 37°C or 42°C, and cell number was determined 72 h later. Bars, s.e.m. *, Heated and unheated treatments significantly different (p<0.01, Student’s t-test).