Candida albicans Increases Tumor Cell Adhesion to Endothelial Cells In Vitro: Intraspecific Differences and Importance of the Mannose Receptor
Figure 4
Differences in expression level of the genes identified in the pro-metastatic mannoprotein fraction.
Expression level of the ten genes studied in different strains (NCPF3153, UPV1360, UPV1413, and CA2) and morphologies, blastoconidia (□) and germ tubes (▪), related to blastoconidia of Candida albicans NCPF3153 (control). Genes: alcohol dehydrogenase (ADH1), aminopeptidase Y (APE3), isocitrate dehydrogenase subunit (IDH2), enolase (ENO1), fructose-bisphosphate aldolase (FBA1), ketol-acid reductoisomerase (ILV5), disulfide isomerase (PDI1), phosphoglycerate kinase (PGK1), ubiquinol-cytochrome-c reductase (QCR2) and translation elongation factor Tu (TUF1). The results shown correspond to the mean ± SD of three independent experiments. Statistically significant differences with respect to the control or between different morphologies are indicated by one (*) and two asterisks (**) (p<0.05), respectively.