Intestinal T-cell Responses in Celiac Disease – Impact of Celiac Disease Associated Bacteria
Figure 1
IL-17A mRNA levels are elevated in patients with active CD.
Expression levels of mRNAs for IL-17A (a), IFN-γ (b), Foxp3 (c) and IL-10 (d) were determined in freshly taken biopsies from the proximal small intestine of pediatric CD patients with untreated, active disease (Untreated CD), CD patients on gluten-free diet with inactive disease (Treated CD) and clinical controls (Controls) using qRT-PCR. Amounts of cytokine and Foxp3 mRNAs were normalized to the 18S rRNA content in each sample. Dots depict expression levels in individual samples. Horizontal bars indicate median values. P-values of statistically significant differences are depicted.