Interaction between Advanced Glycation End Products Formation and Vascular Responses in Femoral and Coronary Arteries from Exercised Diabetic Rats
Figure 6
Nitric oxide (NO) production in femoral and coronary arteries.
Upper panel: Representative fluorographs of DAF-2-treated sections without (BASAL) or with acetylcholine (ACh, 10 µM)-stimulation of femoral (panel A) and coronary (panel B) arteries from control sedentary (C/SD), sedentary diabetic (SD/DB) and trained diabetic (TR/DB) rats. Lower panel: Quantitative analysis of the NO production measured by DAF-2 (delta of ACh integrative density minus basal integrative density) in transverse sections of femoral (panel A) and coronary (panel B) arteries. Data are mean ± SEM. The number of animals per group is indicated in the figure. *p<0.05 compared to C/SD and +p<0.05 compared to SD/DB.