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Evaluation of the Diagnostic Potential of IP-10 and IL-2 as Biomarkers for the Diagnosis of Active and Latent Tuberculosis in a BCG-Vaccinated Population

Figure 3

IL-2/IFN-γ ratio in subjects with active TB (ATB group) and in subjects with latent TB infection (LTBI group).

A. IL-2/IFN-γ ratio in response to TB antigens was significantly higher in LTBI group than in the ATB group (p<0.0001). Horizontal lines indicate the median IL-2/IFN-γ ratio. B. The ROC analysis using subjects with active TB as patients and subjects with latent TB as controls.

Figure 3

doi: https://doi.org/10.1371/journal.pone.0051338.g003