cAMP/Protein Kinase A Activates Cystic Fibrosis Transmembrane Conductance Regulator for ATP Release from Rat Skeletal Muscle during Low pH or Contractions
Figure 2
Influence of lactic acid on interstitial ATP of buffer-perfused soleus muscle of anaesthetised rats.
Effect of lactic acid on interstitial ATP in the absence of inhibitors (A) or in the presence of α-cyano-4-hydroxycinnamic acid (2 mM; B), CFTRinh-172 (20 µM; C) or glibenclamide (200 µM; D). Values are the mean ± SEM of 14–17 values in A, 6 values in B, 7 values in C or 6 values in D. *, significantly different from the pre-control in 1-way repeated measures ANOVA followed by the Bonferroni post-hoc t-test.