Low Mercury Concentration Produces Vasoconstriction, Decreases Nitric Oxide Bioavailability and Increases Oxidative Stress in Rat Conductance Artery
Figure 5
The effect of superoxide dismutase (SOD, 150 U ml−1) on the concentration-response curves for phenylephrine in aortic rings in control (CT) conditions or HgCl2 (A,B).
Results (mean±SEM) are expressed as a percentage of the response to 75 mmol/l KCl. *P<0.05 by ANOVA. Number of animals used in parentheses. (C) Differences in the area under the concentration-response curve (dAUC) in aortic rings cultured in the presence and absence of superoxide dismutase (SOD, 150 U ml−1) under control (CT) conditions or HgCl2. *P<0.05 by Student’s t-test.