Non-Injurious Neonatal Hypoxia Confers Resistance to Brain Senescence in Aged Male Rats
Figure 9
Effects of neonatal hypoxia on the in situ interaction between NR2A and PSD-95 in the hippocampus of 720-day-old male rats.
(A) Quantification of the association between NR2A and PSD-95, as monitored by the Duolink® “proximity ligation” assay: number of dots per cell in CA1 and dentate gyrus (DG) of control and hypoxic male rats (N = 6/group, with a minimum of 230 cells analyzed/group). Note that the interaction in hypoxia group is 1.72 fold increased. (B) Illustrations of in situ association between NR2A and PSD-95 in the CA1 layer and the dentate gyrus (DG) of control and hypoxic rats.