High-Fat Diet Induces Periodontitis in Mice through Lipopolysaccharides (LPS) Receptor Signaling: Protective Action of Estrogens
Figure 4
HFD-induced inflammatory cell infiltrate in gingival connective tissue is modulated by E2 in wild-type mice.
Histological appearance of the gingival tissues with H/E coloration from WT OVX+NCD (A; n = 10),WT OVX+HFD (B; n = 10), WT OVX+NCD+E2 (D; n = 10), and WT OVX+HFD+E2 (E; n = 10). C Magnification of the inflammatory gingival tissue from HFD-fed mice. F. Number of inflammatory cells for each group. *P<0.05, **P<0.01, ***P<0.001 (one-way ANOVA followed by Tukey test). Results are presented as means ± SEM.