Structural Characterization of the Enzymes Composing the Arginine Deiminase Pathway in Mycoplasma penetrans
Figure 1
Conformational changes on the ADI structures upon substrate binding.
(A) Stereo view representation of the superposition of the open active-site of Mycoplasma penetrans ADI (yellow) with closed active-site of the Mycoplasma arginini ADI in complex with arginine (white). ADI residues involved in the substrate binding and catalysis are labeled and shown in stick representation. (B) Stereo view ribbon representation of the superposition between the Mycoplasma penetrans ADI (yellow) with the Mycoplasma arginini ADI in complex with arginine (blue). Three major mobile loops of the ADI structure are labeled.