Metabolic Consequences of High-Fat Diet Are Attenuated by Suppression of HIF-1α
Figure 2
Western blot for HIF-1α in the livers (panel A) and epididymal fat (panel B) of mice with diet-induced obesity (DIO) treated with HIF-1α antisense oligonucleotides (ASO), control ASO (Con) or observed untreated (U) for 8 weeks.
N = 5 per group. Representative samples shown. High fat diet was administered for 12 weeks prior to the ASO treatment and continued during the treatment.