Tolerogenic Dendritic Cells That Inhibit Autoimmune Arthritis Can Be Induced by a Combination of Carvacrol and Thermal Stress
Figure 4
Carvacrol-TS treated BMDC suppress PGIA.
Arthritis was induced by two intraperitoneally immunizations with human PG on days 0 and 21. One day prior to the second PG immunization mice were intraperitoneally injected with 1×106 PG pulsed untreated, TS treated or carvacrol-TS treated BMDC. As a control, mice received only PBS. Arthritis severity expressed as the mean and SEM of at least six mice per group. * (p<0.05) for area under the curve compared to PBS group.