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An Extract of Crataegus pinnatifida Fruit Attenuates Airway Inflammation by Modulation of Matrix Metalloproteinase-9 in Ovalbumin Induced Asthma

Figure 8

CPEE reduces the expression of ICAM-1 and VCAM-1 proteins in lung tissues of mice.

NC; normal control mice treated with PBS only; OVA; OVA-sensitized/challenged mice; Mon; Montelukast (30 mg/kg) + OVA-sensitized/challenged mice; CPEE-1; CPEE (100 mg/kg) + OVA-sensitized/challenged mice; CPEE-2; CPEE (200 mg/kg) + OVA-sensitized/challenged mice. Values are expressed as mean ± SD (n = 6/group). *Significantly different from NC, P<0.05; †significantly different from OVA, P<0.05.

Figure 8

doi: https://doi.org/10.1371/journal.pone.0045734.g008