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Prepulse Inhibition of Acoustic Startle Reflex as a Function of the Frequency Difference between Prepulse and Background Sounds in Mice

Figure 3

An example of the frequency-dependent prepulse inhibition of the ASR.

The background tone frequency was 18 kHz. The frequency of prepulse tone was from 500 Hz higher to 500 Hz lower than the 18 kHz. The ASR magnitude clearly varied with the frequency difference. The light gray bar at the top represents the continuous background tone. The startle is represented by a darkened area, while the prepulse tone is seen between the arrowhead and the offset of the startle sound. The arrowhead represents the onset of the prepulse tone. Δf: the difference of prepulse frequency from the background frequency.

Figure 3

doi: https://doi.org/10.1371/journal.pone.0045123.g003