Annexin A6 Modulates Chick Cranial Neural Crest Cell Emigration
Figure 9
Annexin A6 overexpression leads to precocious loss of molecular markers of adherens junctions.
(A–D) Representative transverse section taken through the midbrain of an embryo electroporated with pCIG-Annexin A6 (green) after 6 (A), 5 (B,C), and 4 (D) hours of incubation and processing by immunohistochemistry for Claudin-1 (A), Cingulin (B), Cadherin6B (C), and N-cadherin (D) (all red), respectively. Arrows denote the loss of proteins on the electroporated side (right) of the neural tube. Scale bar in (A) is 50 µm and applicable to all images. GFP, green; DAPI, blue.