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In Silico Investigations of the Anti-Catabolic Effects of Pamidronate and Denosumab on Multiple Myeloma-Induced Bone Disease

Figure 8

Changes in the density of bone cells, bone volume and the density of MM cells after single anti-catabolic drug treatments.

(a) Changes in osteoblast density after therapies; (b) Changes in osteoclast density after therapies; (c) Changes in bone volume after therapies; (d) Changes in MM-cell density after therapies.

Figure 8

doi: https://doi.org/10.1371/journal.pone.0044868.g008