Corticosteroid Treatment Ameliorates Acute Lung Injury Induced by 2009 Swine Origin Influenza A (H1N1) Virus in Mice
Figure 2
Effects of BJ501 exposure on lung injury and inflammatory responses in weanling C57BL/6 mice.
Weanling C57BL/6 mice were infected with BJ501 at 105.5 TCID50 or mock-infected. A, Lung histological findings of lung tissue in infected C57BL/6 mice. On day 4, 5, and 6 p.i., alveolar spaces were increasingly filled with alveolar epithelial debris, erythrocytes, and inflammatory cells (Δ). Magnification: ×200; B, C, Profiles of IL-6 and TNF-α in BALF samples. *P<0.05 and **P<0.01 compared with AF control. The values are the means ± SEM from five mice.