The Minimal Deneddylase Core of the COP9 Signalosome Excludes the Csn6 MPN− Domain
Figure 1
Bioinformatic identification of two distinct domains within Csn6 (S6MPN and S6CD) in various fungal species.
The Csn6-like proteins from fungal species were identified from multiple genome databases. Species were grouped according to their phyla, and their conserved (dark red/blue) or diverged (light red/blue) domains, MPN and S6CD. White boxes indicate the missing domains. The data is based on the “fungal genome program” of the “DOE Joint Genome Institute” (http://genome.jgi-psf.org/programs/fungi/index.jsf) and the “fungal genome initiative” of the Broad Institute (http://www.broadinstitute.org/scientific-community/science/projects/fungal-genome-initiative/fungal-genome-initiative).