The Retrograde Frequency Response of Passive Dendritic Trees Constrains the Nonlinear Firing Behaviour of a Reduced Neuron Model
Figure 1
Equivalent circuit representation of a DC/AC-RM.
The somatic (left) and dendritic (right) compartments are connected by a coupling conductance, GC. A key difference between DC/AC-RM and DC-RM is that the membrane capacitance is not uniform. Maximum conductances for the active membrane properties based on the dimensionless Morris-Lecar equations are GNa for sodium current, GK,S for somatic potassium current, GCa for calcium current and GK,D for dendritic potassium current. Reversal potentials are ENa, ECa, EK, and ELeak. Passive membrane properties are Cm,S and Cm,D for somatic and dendritic membrane capacitances, Gm,S and Gm,D for somatic and dendritic membrane conductances, and GC for coupling conductance. VS and VD are membrane potentials in the somatic and dendritic compartments.