Re-Expression of IGF-II Is Important for Beta Cell Regeneration in Adult Mice
Figure 3
Intraperitoneal glucose tolerance test.
Islet functional study was performed by taking IP glucose tolerance test (IPGTT). Mice were starved overnight before intraperitoneal injection of glucose at 1.5 mg/g of animal body weight. Results of IPGTT showed both stains did not recover 3 weeks after Myc deactivation, comparing to their wildtype litter mates (A). After 3 month recovery both strains were able to maintain normal blood glucose (B).