Human-Specific SNP in Obesity Genes, Adrenergic Receptor Beta2 (ADRB2), Beta3 (ADRB3), and PPAR γ2 (PPARG), during Primate Evolution
Figure 4
All NHP had Arg64 allele in ADRB3.
A) Restriction map of ADRB3 digested with MvaI for humans and NHP. B) RFLP patterns of PCR product of ADRB3 digested with MvaI for humans and NHP. Lane 1: PCR products of a human; not digested (112 bp). Lane 2: fragments of the human Trp64/Trp64 (61, 34 and 17 bp which was undetectable at this concentration.) Lane3: fragments of human Arg64/Trp64 (95, 61, 34 and 17 bp). Lane 4 to lane 12: fragments from P. troglodytes, G. gorilla, P. pygmaeus, H. agilis, M. mulatta, M. fuscata, M. fascicularis, M. nemestrina, and M. radiata, respectively (95 bp instead of 61 and 34 bp).