Plasma microRNAs, miR-223, miR-21 and miR-218, as Novel Potential Biomarkers for Gastric Cancer Detection
Figure 3
Validation of the plasma levels of miR-223, miR-21 and miR-218 in large scale.
Box plots show the plasma concentrations of miR-223 (A), miR-21 (B), miR-218 (C) and (miR-223×miR-21)/miR-218 (D) in GC patients (GC, n = 70) and healthy controls (NC, n = 70). The lines inside the boxes denote the medians. The whiskers of box plots: Min to Max. Graphs of receiver operating characteristics (ROC) curve show the area under the curves (AUCs) of miR-223 (E), miR-21 (F), miR-218 (G) and (miR-223×miR-21)/miR-218 (H) for distinguishing the GC patients from the healthy controls. The interval between the 5th and 95th percentiles denotes the confidence level and the report results show as Fraction. All assays were repeated three times in duplicates.