DMH1, a Novel BMP Small Molecule Inhibitor, Increases Cardiomyocyte Progenitors and Promotes Cardiac Differentiation in Mouse Embryonic Stem Cells
Figure 7
Low BryT-expressing fraction produces beating EB after Wnt inhibition.
Each table is data from a single experiment showing the percentage of beating aggregates that formed after GFP– fractions were treated with either DMSO control or 1 µM XAV939 to inhibit Wnt signaling. The DMH1-treated GFP– fractions typically form beating aggregates 6 to 8 days after XAV939 addition (Day 10 to Day 12 after initial induction). The percentages increase over time and the efficiency of beating aggregate formation varies with each FACS. The percentages were calculated from the number of beating aggregates and the number of total aggregates for each condition.