Soluble Interleukin-6 Receptor Induces Motor Stereotypies and Co-Localizes with Gp130 in Regions Linked to Cortico-Striato-Thalamo-Cortical Circuits
Figure 2
Stereotypic Behaviors induced by single injection of sIL-6Rα
sIL-6R-induced repetitive stereotypic behavior. Mean (± S.E.M.) activity scores for; (A) Head bobbing, (B) Head bobbing over 20-min intervals, (C) Vertical Stereotypic Moves, (D) Vertical Stereotypic Moves over 20-min intervals, (E) Vertical Stereotypic Episodes and (F) Vertical Stereotypic Episodes over 20-min intervals following single injections of sIL-6R (0, 0.25, 0.5 and 1 µg/mouse, sc). *p = <0.05.