Protective Role of p70S6K in Intestinal Ischemia/Reperfusion Injury in Mice
Figure 5
The effect of rapamycin on cytokine levels in serum and intestinal tissues.
Rapamycin or vehicle was administered then intestinal I/R performed. Blood and intestinal tissues were collected after 6 h of reperfusion for evaluation of TNF-α, IL-6 and IL-1β levels. A. Relative levels of TNF-α in serum. B. Relative levels of TNF-α in intestinal tissues. C. Relative levels of IL-6 in serum. D. Relative levels of IL-6 in intestinal tissues. E. Relative levels of IL-1β in serum. F. Relative levels of IL-1β in intestinal tissues. Results are mean ± SEM, p<0.05 statistically significant, n = 5 mice per group.