Dopamine D4 Receptor Activation Increases Hippocampal Gamma Oscillations by Enhancing Synchronization of Fast-Spiking Interneurons
Figure 5
Spike-phase coupling in non-fast spiking interneurons is unaffected by D4 receptor activation.
A. Example traces of concomitant recordings of non-fast spiking interneurons and LFP oscillations before and after the addition of PD168077. B. Circular histograms based on recordings similar to those in A, indicating the number of action potentials discharged in each phase from −π to π. The radial axis indicates the number of action potentials. The higher and lower histograms represent recordings before and after PD168077 application, respectively. C. Summary bar-diagrams representing mean peak coherence and resultant vector length, respectively (mean ± SEM; kainate recording in black, subsequent recording with PD168077 in grey).