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Drug Discovery Prospect from Untapped Species: Indications from Approved Natural Product Drugs

Figure 3

The route of deriving Gleevec (approved in 2001) from natural product staurosporine.

The right hand side shows the pharmacophoric supposition of CGP 57148 and CGP-52411 [37].

Figure 3

doi: https://doi.org/10.1371/journal.pone.0039782.g003