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Fibroblast Growth Factor 22 Is Not Essential for Skin Development and Repair but Plays a Role in Tumorigenesis

Figure 4

In vitro wound healing.

Scratch wound assay was performed on primary keratinocytes isolated from wild type and fgf22 knockout male back skin. A) Photographs show the migration of wild type and knockout primary keratinocytes to wounded regions of the monolayer culture at 0, 12, 18 and 32 h post wounding. Scale bar (200 µm). B) Wound closure was monitored, photographed and measured at all timepoints after wounding. Error bars represent SEM.

Figure 4

doi: https://doi.org/10.1371/journal.pone.0039436.g004