Cooperative Interaction between the MUC1-C Oncoprotein and the Rab31 GTPase in Estrogen Receptor-Positive Breast Cancer Cells
Figure 1
MUC1 induces Rab31 expression.
A and B. RNA from the indicated MCF-7 (A) and ZR-75-1 (B) cells was analyzed by RT-PCR using primers designed to detect the indicated transcripts (left). RNA was also analyzed for Rab31 mRNA levels by qRT-PCR (right). The results (mean±SD of three determinations) are expressed as relative Rab31 mRNA levels compared to that obtained in the vector cells. C and D. Lysates from the indicated MCF-7 (C) and ZR-75-1 (D) cells were immunoblotted with the indicated antibodies.