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Three Linked Vasculopathic Processes Characterize Kawasaki Disease: A Light and Transmission Electron Microscopic Study

Figure 14

Pleomorphic mono- and binucleated myofibroblasts, abundant RER and SA/C lymphocytes.

A) RER dominates the cytoplasm of this stellate myofibroblast with a complex nucleus and at least two small nucleoli; some actin (A) is present. The matrix contains some shed external lamina (short red arrows) and fine filamentous collagen. There are typical small lymphocytes (L) with high nuclear to cytoplasmic ratios. Case 13, original magnification 1,700×. B) This MF is bi-nucleated and has very dilated, complicated profiles of RER plus actin (A). The loose ECM is dominated by shed external lamina (short red arrows). Case 26, original magnification 5,000×.

Figure 14

doi: https://doi.org/10.1371/journal.pone.0038998.g014