Tumor Infiltrating CD8+ and Foxp3+ Lymphocytes Correlate to Clinical Outcome and Human Papillomavirus (HPV) Status in Tonsillar Cancer
Figure 2
Box plots presenting tumor infiltrating CD8+ and Foxp3+ cells for different groups of TSCC.
A) number of CD8+ TILs, B) number Foxp3+ TILs and C) the CD8+/Foxp3+ cell ratio. “Good” and “poor” denotes clinical outcome. In addition to the four TSCC groups defined in the Methods section, different combinations of groups have also been compared. Thus, “HPV+ good” corresponds to group A; “HPV+ poor” to group B; “HPV− good” to group C; “HPV− poor” to group D; HPV+ to groups A+B, HPV− to groups C+D; “good” to groups A+C; and “poor” to groups B+D. In order to better visualize the details in the lower part of Figure 1C the upper part of the diagram including the upper whisker (at a ratio of 80) was omitted.