Lack of Wdr13 Gene in Mice Leads to Enhanced Pancreatic Beta Cell Proliferation, Hyperinsulinemia and Mild Obesity
Figure 3
Glucose tolerance test (GTT) and Insulin tolerance test (ITT) of Wdr13 knockout mice.
A) GTT at 2 months on normal chow (n = 8–12). B) GTT at 12 months on normal chow (n = 8–10). C) Glucose tolerance test at 6 months on high fat diet (n = 8). D) ITT at 2 months on normal chow (n = 8–12). E) ITT at 12 months on normal chow (n = 8–10). F) Insulin tolerance test at 6 months on high fat diet (n = 8) G) ITT at 9 months on high fat diet (n = 6–8). (+/0 wild type male; −/0 knockout male).